The shooting occurred in the Tornado café in the Arteveldestraat in central Antwerp. Speculation is mounting that the deaths are the result of a settling of accounts between two Albanian gangs.
The incident happened shortly before 8PM. Eyewitness Marc Arnoudts told reporters: "We were sitting by the window of a pub a little further along when I heard at least fifteen shots."
"Then it was dead quiet for a while. We saw a car drive off, while a number of people ran off on foot. Then there were more shots."
A woman was lying in the street seriously injured and there was a guy on the other side of the street. It was very scary in this area at that time."
The incident claimed at least two lives including one 28-year-old Albanian. A further four people have been taken to hospital for treatment. Two are Albanians and a third is a woman passer-by. Two are in a bad way.
Police are now trying to establish the exact circumstances in which the shooting occurred. There are reports of a big row involving a number of Albanians. The killers are on the run.