Genk pushed Simaeys further up field to make up for the absence of Hyland. Torben Joneleit was put into the centre of defence next to Nadson.
Genk hoped for a repeat of their 3-1 win against Anderlecht in Brussels a couple of weeks ago. However, Kanu was going to let that happen.
He made the most of a misunderstanding between the Genk defender Nadson and keeper Lazslo Köteles to put the visitors one up.
Things when from bad to worse for Genk a little later when golden boy Kevin De Bruyne (photo) was forced to leave the field injured.
Anderlecht remained in control and both Matias Suárez and Guillaume Gillet came close to scoring. Anderlecht’s second goal came from Gillet on 31 minutes. The half ended 2-0 to the visitors.
More of the same
The second half saw more of the same with Gillet and Suárez both coming close to making it 3-0.
However, it was Kanu that found the back of the net on 52 minutes. Genk tried desperately to get back into the game. With Buffel coming close to scoring for the Limburgers.
Anderlecht’s fourth goal of the evening came from Tom De Sutter five minutes from time.
Anderlecht is now 7 points clear of second-placed Club Brugge, although this could narrow to 4 points if Club Brugge wins away at AA Gent on Saturday evening.