Mr Kerry arrived in Brussels from Istanbul when he had attended a meeting of the Friends of Syria.
On Monday afternoon John Kerry will meet the Chairman of the European Commission José Manuel Barroso. On Tuesday he will meet with his Russian colleague Sergey Lavrov during a meeting of the NATO-Russia Council.
On Wednesday he will hold a breakfast meeting with the Belgian Foreign Minister Didier Reynders (Francophone liberal) at the prestigious Egmont Palace. He will leave Brussels on Wednesday evening.